Feynman says: "Nature is like a huge infinite board of chess. Science and human mind tries to analyse one small part of this board and tries to extrapolate to the big picture".
What does it mean? It means we are trying to "determine" the solution of a big probabilistic problem. Will it ever work?
The problem space here has fuzzy boundary and mathematics is gradually spanning with distinct boundaries trying to cover the whole space. One section of mathematics breaks and another evolves ever creating new aspects. Is it time to develop new mathematics which "evolves" with the extrapolation of the small section of the chess game?